CGRP Migraine Medications: Complete Guide to Available Treatments
CGRP migraine medications specifically target calcitonin gene-related peptide (CGRP) or its receptors to prevent migraine attacks by interrupting neurogenic inflammation and trigeminovascular activation at the molecular level. Available as monoclonal antibodies for prevention (erenumab, fremanezumab, galcanezumab, eptinezumab) and gepants for acute/bridge therapy (rimegepant, ubrogepant, atogepant, zavegepant), these therapies reduce monthly migraine days by 50%+ for responsive patients. Haven Headache & Migraine Center in San Francisco expertly prescribes and manages CGRP medications through UCNS-certified specialists, offering virtual care with Orange County procedure coordination.
Preventive CGRP Monoclonal Antibodies
Erenumab (Aimovig): Monthly self-injection blocking CGRP receptors. First-in-class therapy approved in 2018.
Fremanezumab (Ajovy): Monthly or quarterly subcutaneous injections targeting the CGRP ligand.
Galcanezumab (Emgality): Monthly self-injection neutralizing CGRP protein.
Eptinezumab (Vyepti): Quarterly 30-minute IV infusion administered by healthcare professionals.
All demonstrate 50-75% responder rates (≥50% migraine day reduction) within 1-3 months.
Acute and Bridge CGRP Medications (Gepants)
Rimegepant (Nurtec ODT): Orally disintegrating tablet for acute treatment and preventive dosing.
Ubrogepant (Ubrelvy): Oral tablet for acute migraine attacks.
Atogepant (Qulipta): Daily oral preventive gepant.
Zavegepant (Zavzpret): Nasal spray for rapid acute relief.
Gepants offer vasoconstriction-free acute treatment unlike triptans.
Who Benefits Most from CGRP Migraine Medications?
Ideal candidates include:
- Episodic migraine (4-14 days/month) failing 2+ oral preventives
- Chronic migraine (15+ days/month) regardless of prior treatment failures
- Patients with cardiovascular risks (no vasoconstriction effects)
- Triptan non-responders or overusers
- Those preferring targeted molecular therapy over broad-spectrum medications
Why Haven Headache & Migraine Center for CGRP Medications?
Haven delivers specialized CGRP management:
- UCNS-certified prescribing authority with therapy optimization expertise
- Virtual medication authorization and patient training
- Local infusion/injection coordination throughout Orange County
- Combination protocols with Botox, neuromodulation, lifestyle coaching
- Proven 5.0-star Google rating for CGRP therapy success
Comprehensive insurance pre-authorization streamlines access.
Frequently Asked Questions About CGRP Medications at Haven
Which CGRP medication works fastest at Haven?
Eptinezumab IV provides benefits within 1 week; subcutaneous options show effects by month 1.
Can Haven patients self-administer all CGRP medications?
Yes, monthly self-injections (Aimovig, Ajovy, Emgality) include virtual training; eptinezumab requires professional IV.
Does Haven combine CGRP medications with other therapies?
Strategic combinations with Botox, Cefaly, or lifestyle interventions maximize results for complex cases.
What if insurance denies CGRP medication coverage through Haven?
Expert appeals process plus cash-pay pricing and patient assistance program enrollment support.
How does Haven monitor CGRP medication effectiveness?
Monthly virtual visits with headache diary review ensure optimal dosing, switching, or combination strategies.
How to Get Started
- Book a Free Intro Call online or by phone
- Complete Your Intake with medical history and symptom details
- Meet Your Specialist virtually within two weeks
- Receive Your Personalized CGRP Medication Plan with insurance guidance
- Continue With Ongoing Care through virtual monitoring and optimization
Access Advanced CGRP Migraine Medications Today
Orange County patients receive Haven Headache & Migraine Center's specialized expertise accessing the full spectrum of CGRP migraine medications with personalized guidance.
Book your consultation today:
Schedule your appointment with Haven Headache & Migraine Center, providing expert virtual care across California.
Office:
Email:
hello@havenheadache.com
Experience precision migraine prevention through targeted CGRP therapy. Start with a free intro call and discover how Haven helps Orange County patients achieve breakthrough relief.