CGRP targeted therapies: the latest in effective, safe migraine medication

Antidepressants, anti-seizure medications, and anti-hypertensive medications are the old guard of medication when it comes to treating headache and migraine. Calcitonin gene related peptide (CGRP) inhibitors are safe, effective, and on average, offer more relief.

Work in 60% of people with migraine

50% reduction in migraine attacks per month

Low risk of side effects

Preventive oral medication, or once-monthly injections

CGRP inhibitors target the root causes of migraines, making them widely effective for a high percentage of people who use the. 70% of patients who take preventive CGRP inhibitors experience a 50% or more reduction of their migraine symptoms monthly.

Oral and nasal medications to alleviate attack symptoms

Oral and nasal CGRP inhibitors, when taken early enough, can also be used to alleviate symptoms of a migraine attack.


Our certified headache specialists evaluate each patient thoroughly to determine if CGRP inhibitors are suitable to treat your migraine symptoms. If determined necessary, our specialists will provide you with a prescription and guide you through the insurance navigation process to make sure the cost is covered.

Black Man taking CGRP monthly auto Injection in thigh


What CGRP inhibitors do you offer?

Preventive: Aimovig (erenumab), Emgality (galcanezumab), Ajovy (fremanezumab), Vyepti (eptinezumab), Nurtec (Rimegepant) every other day, Qulipta (Atogepant)

Acute: Ubrelvy (Ubrogepant), Nurtec (rimegepant), Zavzpret (Zavegepant)

What are the side effects?

Side effects of CGRP inhibitors can vary by medication, but the most common symptom seen is easily treatable constipation. Injection site reactions might occur for injectable medications, but this is rare.

Does insurance cover these medications?

Most insurances cover CGRP inhibitors with a prior authorization from your doctor, or Haven headache specialist.

How can I get started with treatment?

Your Haven headache specialist will discuss treatment options during your first appointment. Depending on what you have tried in the past, you might be a good fit right away for one of these medications, or you might need to try a few other options before starting. Some insurance companies require you to try a few other medications before prescribing a CGRP inhibitor.

How effective are these medications?

~70% of patients with migraine who try CGRPs for three months or more typically experience a 50% reduction in migraine symptoms. And while the science is still fairly new (by medical standards), studies have proven that the effectiveness of CGRP inhibitors tends to increase the longer you are on them.

Still have questions?